Opportunity Information: Apply for PAR 18 206
The Bioengineering Research Grants (BRG) (R01 Clinical Trial Optional) opportunity (Funding Opportunity Number PAR 18 206) is a National Institutes of Health (NIH) discretionary grant program designed to push forward biomedical solutions that sit at the intersection of the life sciences and the physical sciences. The central goal is to support collaborative, multidisciplinary bioengineering efforts that tackle a clearly defined biomedical problem while also speeding up the real-world usefulness of innovative tools, methods, and techniques. In practice, NIH is looking for projects that do more than introduce a clever new technology; they should integrate that technology into a specific biological, translational, or clinical context by optimizing it, validating it, translating it toward practical use, or otherwise accelerating its adoption in research or healthcare settings.
This funding opportunity is structured around the idea that small, focused teams can make major advances when they deliberately combine expertise across disciplines such as engineering, physics, chemistry, computation, and the biological and clinical sciences. Applications may take different scientific approaches, including design-directed work (engineering a solution to a defined need), developmental efforts (refining and improving a method or device), discovery-driven studies (using bioengineering to reveal new biology), or hypothesis-driven research (testing a defined scientific hypothesis using bioengineering approaches). The common thread is an integrative strategy where engineering principles are applied to produce measurable progress on a targeted biomedical challenge, whether the work is primarily basic science, translational research, or clinical practice-oriented.
A notable feature is that clinical trials are optional, meaning applicants can propose projects that do not include a clinical trial, as well as projects that do, when a trial is appropriate and well-justified for the aims. This makes the program flexible for teams working at different stages of the pipeline, from bench-level tool validation through to human studies, provided the proposal remains centered on accelerating solutions through bioengineering collaboration and rigorous evaluation.
Eligibility is broad and intentionally inclusive. In addition to standard academic and research organizations, eligible applicants include state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other Native American tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status; for-profit organizations (other than small businesses) and small businesses; and other eligible entities. The announcement also explicitly highlights a wide range of institution types and community-focused organizations, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, eligible federal agencies, U.S. territories or possessions, and non-U.S. (foreign) organizations. This breadth signals NIH interest in drawing innovation from many sectors and communities, not only traditional biomedical engineering departments.
Administratively, this is an NIH grant mechanism under an R01-style program, categorized as a grant funding instrument, with activity areas spanning education, environment, health, and social services (as reflected in the opportunity listing). The CFDA numbers associated with the announcement include 93.113, 93.172, 93.279, 93.286, 93.393, 93.394, 93.395, 93.396, 93.399, 93.855, 93.856, 93.865, and 93.867, indicating that multiple NIH institutes and centers may participate or that the program aligns with several NIH funding areas. The opportunity record lists an original closing date of 2019-02-07 and a creation date of 2017-11-07; applicants considering this program should verify the current status, active receipt dates, and any updated reissues or related FOAs in NIH systems, since NIH announcements are often renewed or replaced over time.
In essence, BRG (R01 Clinical Trial Optional) is aimed at teams that can convincingly show (1) a real biomedical problem in need of a solution, (2) a bioengineering-driven plan that depends on cross-disciplinary collaboration, and (3) a pathway to integrate and validate a promising approach so it can be adopted faster and more reliably by researchers or clinicians. The strongest proposals typically make clear why the problem requires an engineering-life science partnership, what concrete deliverables or performance benchmarks will demonstrate progress, and how the work will move beyond a proof-of-concept toward a tool, method, or technique that is ready to be used and trusted in a specific scientific or clinical setting.Apply for PAR 18 206
- The National Institutes of Health in the education, environment, health, income security and social services sector is offering a public funding opportunity titled "Bioengineering Research Grants (BRG) (R01 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.172, 93.279, 93.286, 93.393, 93.394, 93.395, 93.396, 93.399, 93.855, 93.856, 93.865, 93.867.
- This funding opportunity was created on 2017-11-07.
- Applicants must submit their applications by 2019-02-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Applicants also applied for:
Applicants who have applied for this opportunity (PAR 18 206) also looked into and applied for these:
| Funding Opportunity |
|---|
| Bioengineering Research Partnerships (U01 Clinical Trial Optional) Apply for PAR 18 208 Funding Number: PAR 18 208 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Small Research Grant Program (Parent R03 Clinical Trial Not Allowed) Apply for PA 18 488 Funding Number: PA 18 488 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $50,000 |
| Countermeasures Against Chemical Threats (CounterACT) Research Centers of Excellence (U54 Clinical Trial Optional) Apply for PAR 18 657 Funding Number: PAR 18 657 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $2,000,000 |
| Research on the Health of Transgender and Gender Nonconforming Populations (R21 Clinical Trial Optional) Apply for PA 18 728 Funding Number: PA 18 728 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $200,000 |
| Research on the Health of Transgender and Gender Nonconforming Populations (R01 Clinical Trial Optional) Apply for PA 18 729 Funding Number: PA 18 729 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Blueprint Program for Enhancing Neuroscience Diversity through Undergraduate Research Education Experiences (R25) Apply for RFA NS 19 007 Funding Number: RFA NS 19 007 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Blueprint Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award (F99/K00) Apply for RFA NS 19 011 Funding Number: RFA NS 19 011 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Limited Competition: Restoring Research Resources Lost or Damaged Due to Hurricanes Harvey, Irma, and Maria (R24 Clinical Trial Optional) Apply for RFA OD 18 102 Funding Number: RFA OD 18 102 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Short Courses on Innovative Methodologies and Approaches in the Behavioral and Social Sciences (R25 Clinical Trial Not Allowed) Apply for RFA OD 19 012 Funding Number: RFA OD 19 012 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $200,000 |
| NIH Pathway to Independence Award (Parent K99/R00 Independent Basic Experimental Studies with Humans Required) Apply for PA 19 090 Funding Number: PA 19 090 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Quantitative Research Development Award (Parent K25 - Independent Basic Experimental Studies with Humans Required) Apply for PA 19 089 Funding Number: PA 19 089 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Basic Experimental Studies with Humans Required) Apply for PA 19 087 Funding Number: PA 19 087 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Clinical Scientist Research Career Development Award (Parent K08 - Independent Basic Experimental Studies with Humans Required) Apply for PA 19 086 Funding Number: PA 19 086 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Limited Competition: NeuroImaging Tools and Resources Collaboratory (R24 Clinical Trial Not Allowed) Apply for RFA EB 18 004 Funding Number: RFA EB 18 004 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $600,000 |
| HEAL Initiative: HEALthy Brain and Child Development Study (HEALthy BCD) (Collaborative R34- Clinical Trial Not Allowed) Apply for RFA DA 19 029 Funding Number: RFA DA 19 029 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $225,000 |
| Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed) Apply for PAR 19 134 Funding Number: PAR 19 134 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $300,000 |
| HEAL Initiative: HEALthy Brain and Child Development Study (HEALthy BCD) ( R34- Clinical Trial Not Allowed) Apply for RFA DA 19 036 Funding Number: RFA DA 19 036 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $225,000 |
| Limited Competition for a Connectome Coordination Facility (R24 Clinical Trial Not Allowed) Apply for RFA MH 20 210 Funding Number: RFA MH 20 210 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $900,000 |
| Transformative Research Award for the INCLUDE (Investigation of Co-occurring Conditions across the Lifespan to Understand Down syndrome) Project (R01 Clinical Trial Not Allowed) Apply for RFA OD 19 016 Funding Number: RFA OD 19 016 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Clinical Trials Development for Co-Occurring Conditions in Individuals with Down syndrome: Phased Awards for INCLUDE (R61/R33 Clinical Trials Required) Apply for RFA OD 19 018 Funding Number: RFA OD 19 018 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
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