Opportunity Information: Apply for RFA HL 17 034
Revision Applications for Regenerative Medicine Innovation Projects (RMIP) (U01) is a National Institutes of Health (NIH) funding opportunity, developed with participation from multiple NIH Institutes and Centers and in collaboration with the U.S. Food and Drug Administration (FDA), that targets a very specific type of request: a competing revision to an already-active U01 cooperative agreement. In practical terms, this FOA is not meant for brand-new stand-alone projects. It is designed for investigators who already hold an active U01 research project award and who want additional funds during the current budget period to expand the approved scope of work or to add to or modify the existing research protocol. The overall goal is to accelerate progress in regenerative medicine clinical research that uses adult stem cells by supporting focused, high-impact expansions that can solve recognized bottlenecks in developing regenerative medicine therapies.
The scientific emphasis centers on innovation that directly addresses well-known challenges in creating regenerative medicine products that are both safe and effective. The FOA strongly prioritizes projects that tackle product development issues that matter for regulatory submissions, reflecting FDA involvement and the program’s translational intent. Rather than basic discovery alone, the revisions are expected to produce practical solutions such as improved tools, methods, standards, or applied scientific approaches that make it easier to manufacture, characterize, test, and evaluate regenerative medicine products. The scope of interest includes, but is not limited to, advances that strengthen understanding and assessment of manufacturing processes, product quality, safety profiles, and measures of effectiveness, especially in ways that can support or de-risk later regulatory interactions and filings.
From an administrative standpoint, this opportunity is issued by the U.S. Department of Health and Human Services (HHS) through NIH. The funding instrument is a cooperative agreement (U01), which typically indicates substantial programmatic involvement by NIH staff compared with a standard research grant. The opportunity is listed as discretionary and falls under the health-related funding activity category (Food and Nutrition, Health). The Funding Opportunity Number is RFA HL 17 034, and the posting information indicates it was created on April 28, 2017, with an original application due date of June 26, 2017.
The eligible applicant pool is broad and spans many organizational types, including state, county, and city governments; special district governments; independent school districts; public and private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status; for-profit organizations other than small businesses; small businesses; and other entities as allowed under the FOA’s additional eligibility language. This broad eligibility matters mainly as a structural allowance, but the key functional eligibility constraint remains that applicants must be investigators with active U01 awards appropriate for a competing revision under this program.
In terms of anticipated funding scale and competition, the FOA lists an award ceiling of $324,500 and an expected number of awards of 6. Those figures suggest a targeted, selective program focused on discrete expansions of ongoing U01 projects rather than large numbers of new awards. Overall, the opportunity can be understood as a mechanism to inject additional, purpose-driven resources into existing adult stem cell-based clinical research projects so they can address the kinds of manufacturing, quality, safety, and effectiveness evaluation issues that commonly slow down translation and complicate regulatory readiness in regenerative medicine.Apply for RFA HL 17 034
- The Department of Health and Human Services, National Institutes of Health in the food and nutrition, health sector is offering a public funding opportunity titled "Revision Applications for Regenerative Medicine Innovation Projects (RMIP) (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121, 93.173, 93.233, 93.242, 93.286, 93.350, 93.837, 93.838, 93.839, 93.840, 93.846, 93.847, 93.853, 93.855, 93.856, 93.866, 93.867.
- This funding opportunity was created on Apr 28, 2017.
- Applicants must submit their applications by Jun 26, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $324,500.00 in funding.
- The number of recipients for this funding is limited to 6 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Applicants who have applied for this opportunity (RFA HL 17 034) also looked into and applied for these:
| Funding Opportunity |
|---|
| Revision Applications for Regenerative Medicine Innovation Projects (RMIP) (P41) Apply for RFA HL 17 033 Funding Number: RFA HL 17 033 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $324,500 |
| Cystic Fibrosis Research and Translation Center (P30) Apply for RFA DK 17 007 Funding Number: RFA DK 17 007 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $750,000 |
| NIDDK Information Network Coordinating Unit: dkNET-CU (U24) Apply for RFA DK 17 010 Funding Number: RFA DK 17 010 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $635,000 |
| Limited Competition for the Continuation of the Drug Induced Liver Injury Network Data Coordinating Center (U24) Apply for RFA DK 17 510 Funding Number: RFA DK 17 510 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $900,000 |
| Limited Competition for the Continuation of the Drug Induced Liver Injury Network (DILIN) Clinical Centers (U01) Apply for RFA DK 17 509 Funding Number: RFA DK 17 509 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $250,000 |
| Chronic Kidney Disease in Children Central Biochemistry Laboratory (U24) Apply for RFA DK 17 034 Funding Number: RFA DK 17 034 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $250,000 |
| Catalyst Award in Diabetes, Endocrinology and Metabolic Diseases (DP1- Clinical Trial Not Allowed) Apply for RFA DK 17 011 Funding Number: RFA DK 17 011 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $500,000 |
| NIDDK Partnerships with Professional Societies to Enhance Scientific Workforce Diversity and Promote Scientific Leadership (R25) Apply for RFA DK 17 015 Funding Number: RFA DK 17 015 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $135,000 |
| Diabetic Foot Consortium - Clinical Research Units (U01) Apply for RFA DK 17 014 Funding Number: RFA DK 17 014 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $275,000 |
| Lymphatics in Health and Disease in the Digestive System (R01 - Clinical Trials Not Allowed) Apply for RFA DK 17 016 Funding Number: RFA DK 17 016 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $499,999 |
| Multidisciplinary Urologic Research (KURe) Career Development Program (K12 Clinical Trial Optional) Apply for RFA DK 17 012 Funding Number: RFA DK 17 012 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $600,000 |
| George M. O'Brien Urology Cooperative Research Centers Program (U54-Clinical Trial Optional) Apply for RFA DK 17 013 Funding Number: RFA DK 17 013 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $1,000,000 |
| Silvio O. Conte Digestive Diseases Research Core Centers (P30 Clinical Trial Optional) Apply for RFA DK 18 001 Funding Number: RFA DK 18 001 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $750,000 |
| Funding For Collaborative Clinical Research In Type 1 Diabetes: Living Biobank (R01 Clinical Trial Optional) Apply for RFA DK 17 032 Funding Number: RFA DK 17 032 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $600,000 |
| Elucidating the Effect of Glycemic Excursions on Patient Well-being and Cognitive Status in People with Type 1 Diabetes (T1D) (R01 Clinical Trial Optional) Apply for RFA DK 18 003 Funding Number: RFA DK 18 003 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $500,000 |
| Undergraduate Summer Research Education in Kidney, Urologic, and Hematologic Diseases (R25 Clinical Trial Not Allowed) Apply for RFA DK 18 006 Funding Number: RFA DK 18 006 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $125,000 |
| Human Islet Research Enhancement Center for the Human Islet Research Network (U24 Clinical Trial Not Allowed) Apply for RFA DK 18 012 Funding Number: RFA DK 18 012 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $1,200,000 |
| Ancillary Studies to the NIDDK Inflammatory Bowel Disease Genetics Consortium (R01- Clinical Trial Optional) Apply for RFA DK 18 017 Funding Number: RFA DK 18 017 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $200,000 |
| Lymphatics in Health and Disease in the Digestive System (R01 Clinical Trial Not Allowed) Apply for RFA DK 18 021 Funding Number: RFA DK 18 021 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $250,000 |
| Data Coordinating Center for the Diabetic Foot Consortium (U24 Clinical Trial Not Allowed) Apply for RFA DK 18 010 Funding Number: RFA DK 18 010 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $500,000 |
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